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Lecture 7

Lecture 7 notes.

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Ted Petit

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Lecture 07 Mechanisms of Drug Action, Psychopharmacology of Neural Stimulants Individuals who use drugs for themselves for fun (self-induced drugs) Addiction is a huge problem in North America, hence important to be aware of the drugs Global Overview of Types of Drugs: Prescription drugs o The laws regarding prescriptions vary by country, decade, etc. (Legalities vary between countries) Over the counter drugs Social drugs (nicotine, caffeine, alcohol). Not from a drug store or prescribed. Drugs that are not produced commercially (marijuana) or produced commercially but not for psychoactive effects (such as airplane glue) Tolerance, Addiction & Withdrawal Tolerance Most drugs if taken repeatedly results in a decreasing behavioural affect o Why? Stimulates the post-synaptic neuron. The more the receptors are bombarded, the more it responds by reducing the number or sensitivity of post-synaptic receptors o Once this occurs, it will not fire as often o Thus you have developed tolerance to the drug (though never a permanent thing) o No longer relaxing the brain as much o The brain responds to certain drugs more rapidly than others o A depressor results in extra receptors being developed on the post-synaptic cell Withdrawal Withdrawal effects can be very severe
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