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Psychology (7,782)
PSYB65H3 (519)
Ted Petit (310)
Lecture 6

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Ted Petit

PSYB65 Lecture 6Psychiatric DisordersSchizophrenia most commonly associated with hallucinations and delusions age of onset is from early 20s to about 30 neuropsychological tests show that people with schizophrenia in frontal lobe tests as well as tests of memory verbal or nonverbal and most other neuropsychological tests show that they are completely normal do show enlarged ventricles and lighter brain weight genetic studies 1 of the population is schizophrenic 1015 of immediate family is schizophrenic dizygotic twins had 1015 concordance monozygotic twins had 4075 concordance antihistamines had a calming effect on patients the drugs that were most effective were dopamine antagonists reduce functional activity of dopamine particularly phenothiazine and within that class chlorpromazinebeing the most commonly usedeffectivethese drugs blocked the receptor sites for the biogenic aminesmonoamines such as norepinephrine dopamine and serotonin the ones that blocked dopamine receptors were the most effective dopamine stimulants such as amphetamines could do two things cause schizophrenic symptoms in completely normal individuals no difference in the amount of dopamine in the brains of schizophrenic patients from normal persons the difference was in the number of dopamine receptors D4Mood DisordersDepression and ManiaEarly research was done again by mistake they gave people blood pressure medication Aldomet was the primary one that was used which caused people to get depressedthese chemicals caused a reduction in the monoamines biogenic amines the big one was reserpine which caused the monoamines to leak from the
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