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PSYB65 chapter 14.docx

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University of Toronto Scarborough
Ted Petit

Chapter 14Tumor mass of new and abnormal tissue that is not beneficialo Also called neoplasms new tissue o Space occupying lesions foreign objects that cause damage to CNSBrain most common site uterus secondTumors differ in growth rate whether they infiltrate or stay encapsulated or how likely to recur if removedBenign wont recurMalignant more likely to recur3 major types of brain tumours originate from glial cells the meninges nervous tissue or other parts of the body already infected with a tumor o From glial cellsgliomasAstrocytomas from astrocytes Grow slowly and rarely malignant Causes compression of surrounding tissue Some infiltrate surrounding tissue Usually surgically removed unless its inaccessibleGlioblastoma grow quickly highly malignant Infiltrates surrounding tissue Hard to surgically removechemotherapy is often treatment insteadMedullablastoma Highly malignant forms around cerebellum and brainstem early in life so it affects vegetative functions Prognosis is poor Chemotherapy best option o From meningesMeningiomas gorow out from meninges From dura mater Outside of CNS therefore well encapsulated Harmful when pressure applied from tumor Relatively benign Surgery best treatment o Metastatic tumors secondary tumors from migrated tumor Can be lungs breasts uterus kidneys More common for original tumor to be located outside of CNSSimple metastatic one tumorMultiple metastatic tumors more spread from lungs to CNSSurgical or radiological treatment If multiple than whole brain radiotherapy or chemotherapyPrognosis poorNeuropsychological effects small slow infiltrating astrocytoma in primary visual cortex can slowly cause nlndness in part of visual field Same with tuomrs of pituitary gland because its close to optic chiasmRapid meningioma that is encapsulated can apply pressure to primary motor and sensory corticies causing paresis and numbess to feet and legsMetastatic tumors in left temporal lobespeech distruabnces left parietal lobeapraxia Tumors can also cause epileptic seizues and release substances toxic to brain If in ventricles it can be spread
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