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Lecture 10

Lecture 10

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Ted Petit

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Lecture 10 - FRONTAL LOBE: - The posterior portion deals with the primary motor strip - Anterior to the primary motor strip is the association cortex dealing with higher order function: planning, socially appropriate behaviour - One of the areas hit hardest is the frontal lobe in Alzheimers. - You dont always get all of the symptoms for a disease because it is dependent on the size location of the tumor. You only find all the symptoms if the person was in a sever accident. - What happens in individuals who have frontal lobe lobotomies (frontal lobe removed) - - HISTORY OF FRONTAL LOBOTOMIES: - Prefrontal area (anterior portion of the frontal lobe) - Gall brought in the concept of phrenology (use the skull to determine personality). Based the distinction on individuals who had the characteristics. Gall thought the anterior portion of the frontal lobe had to be with intelligence. - In 1930s Jacobsen decided that he was going to test phrenology theory in monkeys. He took a series of monkeys and trained and tested them in a series of behavioural tests. Then he took the monkeys and removed the prefrontal area (frontal lobotomy). He found that his monkeys had a loss of delayed response capabilities. They could not perform if there was a delay between seeing a solution to a problem and actually being able to perform that problem Wisconsin General Testing Apparatus (WGTA): a monkey sitting at a table and infront is a screen and a little hole between money and human. So the monkey can see which cup the human is putting the treat in. The close the blinds so the animal cant respond right away (there is a delay). Then they were allowed to pick and they couldnt pick the right one. Normal monkeys when trying to get a banana and couldnt reach they would go get a tool to get the banana. But missing prefrontal lobe would go to the tool but forget what they were doing so there was a delay and thus couldnt perform. If he left the animals in the dark during this intermediate period, when the animals is supposed to be thinking about how to solve the problem, or if given sedative such as a barbiturate the animals were able to solve the problem. He found the problem was not in memory but in distractibility. So if in the dark then he could remember the task because there wasnt other things distracting or emotionality. He also found, the animals had problems in alternation. The raisin always goes underneath the red cup. He gets 10 choices where it is correct. The 11 choice you put it in the blue cup but monkey reaches for the red cup. The next time he will grab the red cup. The monkey
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