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Lecture 4

PSYC23H3 Lecture 4 Glucocorticoids.docx

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David Haley

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Hunger and Memory Protein - brain will work – synapses How body make decisions under this complex conditions Mild hunger – a little bit long study hours might be condusive Pavlovian Conditioning Early mechanisms of learning – biology figure out best stragtegy of survival Forming assoc. bet. Neutral stimulus and food (desire) easy to understand every time hear NS – bell then expect food Threat Det. (Fear learning) Amygdala plays crucial role in determining fear Amygdala calcified no have amygdala – Urbach Wiethe disease Instinctual fear – not enough exposure – consciously afraid No amygdala no fearful response that directs that behavior Stress system Amygdala detecting threat in env. HPA sys. And starts sending signals designed to deal with threat Learn these chemicals that being release in level of these axes Immediate effects of having HPA system activated once you detect threat Good Memories of Bad Eventsin Infants Why baby rats approach noxious sit. Than avoid? Neonatal rat expose in odor and shot Transitition in Infant learning are modulated Glucocorticoids – GCs – cortisol in animals inject then avoidance behavior Dopamine blocker – back to approach odor Cortisol acting on dopa receptor that is going to produce fearful learning or avoidance behavior HPA axis – remove adrenals where cortisols is secreted no more cortisols Chronic Stress Triggers Social Aversion Stress influence avoidance behavior – chronic stress and triggers social aversion – specific with how this works Cage with aggressive animals – RATS – scary 5mins exposure is one thing but in next 24 hours sleep with them there is wall – stress system active - activate dopaminergic system 0 long term outcomes months later expose to novel person – after 10 days to thataggression – high stress reaction i
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