ANA300Y1 Lecture Notes - Lecture 17: Stratum Granulosum, Stratum Corneum, Fascia
Document Summary
Below the skin is the subcutaneous layer (not part of the skin) called hypodermis or superficial fascia is separate. Accessory structures of skin: hair (some skin has hair on it), nails (finger nails and toe nails), exocrine glands associated with skin (temperature regulation or lubrication) As you go up you get spiny cell layer, cells end up with spines sticking around them end up prickly stratum granulosum, packed full of granules so appear dark stratum corneum where cells all dead. Keratinocytes begin to produce keratohyalin (protein that associate with keratin)granules. Stratum spinosum spikes coming out of cells all the way around spiny layer, these desmosomes cause them to still hold on to each other which gives appearance of spines with fixation. If thick skin you have stratum lucidum in thick skin only, dead cells a dense layer of flattened protein-packed cells.
