ANT208H1 Lecture : lec 10 med ant.docx

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17 Apr 2012
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Major human pathogens and host pathogen coevolution: environmental co-factors +historical influences are key in changing risks in infection and chances of survival through morbidity by these diseases. Evolved defence against pathogens and pathogen strategies: immune response +pathogen counter adaptations. Biocultural interactions: technological efforts, extermination of vectors, poverty, tools are not applied everywhere, => social diseases, that"s why some populations have more diseases than others. Intrinsic mortality: benefit from shutting things down(senescence: biotic risks(source and level for humans): Good for microorganisms defence: hormonal control of threat response, social grouping/exclusion;cooperation/warfare etc, theory of mind . Communicable diseases vs ncds"s = caused by microorganisms that use another individual"s resources to feed,grow,reproduce and provoke immune response +/- disrupting function: causes immune response,disrupts function at some point. Our guts do not provoke immune system or affect our system: attribution of disease to infection:germ theory, koch"s 4 postulates: focus on pathogenicity. Host+environment also key: types of pathogen. Most illness and eath caused by a few.

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