ANT208H1 Lecture Notes - Lecture 9: Epidemiological Transition, Hygiene Hypothesis, Antigenic Shift
Document Summary
No dna or rna, so transmission is unclear: form masses of fibrils which might cause adjacent protein to fold into similar shapes. Examples: mad cow disease, familial insomnia, cjd. Good at helping to shield our bodies by creating a different environment: stomach ph. Acidity of our stomachs can deter some pathogens but some work pretty well in the stomach: expelling. Retain iron and not let it into our system if we are sick. Pathogens can adapt to exploit these responses. Three jobs: pathogen recognition, pathogen destruction o. Monitor the intercellular areas and important in cellular response. Innate immune system: primitive system, recognition of generalized markers common among pathogens but not among hosts. Adaptive immune system: derived system (vertebrates, recognition of specific epitopes or (antigenic determinants, antigens. Hiv/aids is good at getting into the white blood cells and then circumvents the white blood cell systems.
