BIO120H1 Lecture Notes - Lysosome, Membrane Transport, Leucine

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2 Feb 2013
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BIO120H1 Full Course Notes
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BIO120H1 Full Course Notes
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We"re going to look at sorting of proteins into different intracellular compartments. We"ve been looking at the movement of small molecules across the different membranes in a cell but the proteins also need to move to the different compartments in order for the compartments to have their specific functions. For example, the er, the golgi, the peroxisome and the nucleus all need specific proteins in order to maintain their proper functions. For example you can imagine that a transcription factor needs to get to the nucleus in order to transcribe dna into rna so that transcription factor needs to be sorted to the nucleus in order to function properly. For example, the mitochondria & we"re going to look at cytosolic proteins, the peroxisomes, the er, & of course the nucleus. We"re also going to look at the nucleus & how proteins also get into & out of cells.

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