BIO120H1 Lecture Notes - Lecture 8: Exocytosis, Copii, Copi
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BIO120H1 Full Course Notes
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This is the next lecture, this is about sorting and packaging of proteins in the golgi apparatus. Just an overview, this is basically to remind us of how proteins destined for the secretion pathway actually go through this process and we"ll see a little movie of this in a bit. Basically all proteins or most of them are transcribed, the genes are transcribed in the nucleus and then translated in the cytoplasm and proteins that are destined for secretion are transported into the er shown on the slide. Recognize or appreciate that both soluble proteins & transmembrane proteins are going through this secretion process. So the 1st destination from the er is the golgi and that is what we"re going to cover today and this movie nicely shows what we learned so far about secretion and where we"re going to. Fluorescently labeled membrane proteins start their journey to the plasma membrane after synthesis in the er.
