BIO120H1 Lecture Notes - Protein Structure, Hydrolysis, Release Factor
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BIO120H1 Full Course Notes
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Firstly, remember that trna brings aas to the ribosomes. The trna is the one that recognizes the mrna through anticodon to codon pairing. If you think about this the trna already has an aa attached. You have to make sure that you have the right aa attached to the right trna otherwise you"re in trouble. What it means is that you need to have 20 different enzymes, 20 different trna synthases each of the 20 trnas binds to a particular aa. Diagram: trna that binds to a tryptophan this particular trna synthase only binds to trp, as well it binds to any transfer rna that has an anticodon that recognizes the codon for tryptophan. Recall: for the degeneracy inherent in dna, there is a subset of trna that will have the correct anticodon. In the case of tryptophan there is only one but for others there may be subsets/replacements.
