BIO120H1 Lecture 5: Lecture 5- Maintenance and Measurement of Genetic Variety
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Lecture the maintenance & measurement of genetic variation: what processes influence the maintenance of genetic variation in populations, how do we measure genetic variation and how it exists in a population. 1930-50 theoretical population genetics was initiated by fisher, haldane & wright and provided the foundations for neo-darwinism and the new synthesis . They showed that continuous variation and darwinian natural selection were entirely consistent with mendel"s laws. They also demonstrated the evolutionary significance of genetic variation leading to several key questions and development of the field of ecology & evolutionary genetics. Proportion of gene loci that are polymorphic. Gene is variable; more than one type of allele. Average frequency of heterozygous individuals per gene locus (a site on a chromosome that is usually a gene) What processes influence patterns of genetic diversity: mutation; Caused by random errors during replication: recombination. Introduces new combinations of mutations into a population: random genetic drift.