BIO120H1 Lecture : Notes taken during lecture

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2 Feb 2011
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BIO120H1 Full Course Notes
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BIO120H1 Full Course Notes
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Intracellular vesicular transport part 1 and molecular mechanisms. Proteins today all synthesize into er lumen or. Golgi has series of membrane stacks/pancakes there are resident proteins in each stack. ceramide more minor component made in er transported to other compartments in vesicles: synthesized in er, transported into golgi, where it is modified to produce. glycolipids sugars attached to fat happens in golgi. Do not need to memorize the chemical pathway. enzymes labelled in green in cytosol or are transmembrane membranes with acive sites in cytosol. occurs in cytosol *** cytosolic leaflet will grow, made by er expansion : plasma membrane expands lipids from er, new lipids in cytosolic leaflet of er . Newly synthesized lipids inserted into cytosolic leaflet luminal leaflet a bit smaller not stable so some lipids in cytsolic leaflet flipped into other leaflet. scramblase : so random distribution in er membrane.

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