Class Notes (923,814)
CA (543,272)
UTSG (45,887)
BIO (2,271)
BIO120H1 (1,175)
Lecture

Notes taken during lecture

3 Pages
104 Views

Department
Biology
Course Code
BIO120H1
Professor
Jean Jiang Nash

This preview shows page 1. Sign up to view the full 3 pages of the document.
LECTURE 10
Cell communication
Unicellular organism
Signal transduction cascade
EGF receptor is the receptor tyrosine kinase
Feeds into nucleus to alter transcription
A NETWORK not linear
Why is signalling important?
Cyclic AMP
oNucleotide secreted by single celled organism, slime mold
In rotting log in forest
Divide and take over the log
Eventually run out of nutrients, secrete cyclic AMP
Cyclic AMP attracts each other, so all mold gets together into a
slug and move out of wood
This organism is at the edge of unicellular and multicellular
Two types of cells stalk and spores spore flies away stalk dies
Get together because they’re attracted to cAMP
Cell migrates towards the source outside the cell
Cell receives cAMP, activates PI-3 kinase
oActin polymerases and pseudopods pushes out, so movement
Signal molecules and receptors
Hydrophilic ligands
oCan move around in extrcelluar fluid
oOr secreted from one cell and move by diffusion to another
Hydrophoblic signalling molecules
oEg. Glucocorticoid
Classes of cell surface receptors in animals
E.g. visual, taste, smell receptors
Cytosolic domain has enzymatic activity or is associated with an enzyme
Or associated with an enzyme
o(see the figure 15-16)
Built into receptor or not built into receptor
Important roles in animal development
oExtremely important
oSpecifying cell types
Roles in development, growth, disease resistance
Receptors for plant hormones
Intracellular signalling pathways
www.notesolution.com

Loved by over 2.2 million students

Over 90% improved by at least one letter grade.

Leah — University of Toronto

OneClass has been such a huge help in my studies at UofT especially since I am a transfer student. OneClass is the study buddy I never had before and definitely gives me the extra push to get from a B to an A!

Leah — University of Toronto
Saarim — University of Michigan

Balancing social life With academics can be difficult, that is why I'm so glad that OneClass is out there where I can find the top notes for all of my classes. Now I can be the all-star student I want to be.

Saarim — University of Michigan
Jenna — University of Wisconsin

As a college student living on a college budget, I love how easy it is to earn gift cards just by submitting my notes.

Jenna — University of Wisconsin
Anne — University of California

OneClass has allowed me to catch up with my most difficult course! #lifesaver

Anne — University of California
Description
LECTURE 10 Cell communication Unicellular organism Signal transduction cascade EGF receptor is the receptor tyrosine kinase Feeds into nucleus to alter transcription A NETWORK not linear Why is signalling important? Cyclic AMP o Nucleotide secreted by single celled organism, slime mold In rotting log in forest Divide and take over the log Eventually run out of nutrients, secrete cyclic AMP Cyclic AMP attracts each other, so all mold gets together into a slug and move out of wood This organism is at the edge of unicellular and multicellular Two types of cells stalk and spores spore flies away stalk dies Get together because theyre attracted to cAMP Cell migrates towards the source outside the cell Cell rece
More Less
Unlock Document


Only page 1 are available for preview. Some parts have been intentionally blurred.

Unlock Document
You're Reading a Preview

Unlock to view full version

Unlock Document

Log In


OR

Don't have an account?

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit