BIO120H1 Lecture : Notes taken during lecture

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redtermite204

8 Mar 2011

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BIO120H1 Full Course Notes

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Cytoskeletal networks are dynamic especially microtubules, which can lengthen and shorten. but there are others who are not dynamic, but static. 3 types: anchoring junctions like velcro; occluding junctions like ziploc; anchoring junctions: mechanically attach cells to cells or the extracellular matrix . occluding junctions: seal the contacts between cells : prevents material from passing btw cells. channel forming junctions: allow small molecules to pass from cell to cell . circle is the cell on average, 50 micrometres across: dot beside it is a protein, a cell adhesion protein. to adhere cell to adjacent cell, to adhere to the matrix. cell adhesion proteins are clustered into groups, which increase strength of interaction between cell: many stronger than one, velcro effect, pulling on whole network, not just hydrophobic interaction. affinity: the binding strength between two molecules via a single binding site .

Related Questions

Match the following choices to the statements.

1) Formed by proteins that create tunnels between cells

a) Adhesion Belts

b) none are correct

c) desmosomes

d) gap junctions

e) tight junctions

2) A site of linkage between the extracellular matrix and the cytoskeleton

a) Adhesion Belts

b) none are correct

c) desmosomes

d) gap junctions

e) tight junctions

3) A site of linkage between the actin cytoskeleton of two adjacent cells

a) Adhesion Belts

b) none are correct

c) desmosomes

d) gap junctions

e) tight junctions

4) Rely on intermediate filaments to connect cells to an adjacent cell

a) Adhesion Belts

b) none are correct

c) desmosomes

d) gap junctions

e) tight junctions

5) Are non-functional in patients with a genetic disorder known as Pemphigus vulgaris

a) Adhesion Belts

b) none are correct

c) desmosomes

d) gap junctions

e) tight junctions

6) Are abundant in tissues that experience high mechanical stress (e.g., heart muscle)

a) Adhesion Belts

b) none are correct

c) desmosomes

d) gap junctions

e) tight junctions

1. How does the extracellular matrix affect a cell that it surrounds? (Select all that apply.)

	The cell's shape depends in part on the structure and composition of the extracellular matrix.
	The genes that the cell expresses depend in part on the types of proteins in the extracellular matrix.
	The size that the cell grows to depends in part on the polysaccharides in the extracellular matrix.
	The extracellular matrix has no effect on the cells that it surrounds.
	All of these choices are correct.

2. Which of the following enable(s) the movement of cells?

	microtubules
	microfilaments
	intermediate filaments
	microtubules and microfilaments
	microfilaments and intermediate filaments

3. Microtubules increase in length:

	more quickly at one end than the other.
	by growing outward from the centrosome.
	in cycles, following rapid depolymerization.
	if free tubulin dimers are available.
	All of these choices are correct.

4. Dynamic instability is the rapid assembly and disassembly of:

	microfilaments.
	intermediate filaments.
	microtubules.
	both microfilaments and microtubules.

5. Which one of the following is a characteristic shared by integrins and cadherins?

	Both are peripheral membrane proteins.
	Both facilitate the adhesion of cells to extracellular matrix proteins.
	Both are present in adherens junctions, desmosomes, and hemidesmosomes.
	The cytoplasmic domains of both proteins are connected to the cytoskeleton.

6. Cadherin is an example of a(n):

	motor protein.
	intermediate filament protein.
	cell adhesion molecule.
	extracellular matrix protein.

7. Which is the CORRECT order from lesser to greater complexity for the following?

	organs, tissues, cells
	cells, tissues, organs
	tissues, organs, cells
	cells, organs, tissues

pucebear535

1. How does the extracellular matrix affect a cell that it surrounds? (Select all that apply.)

		The cell's shape depends in part on the structure and composition of the extracellular matrix.
		The genes that the cell expresses depend in part on the types of proteins in the extracellular matrix.
		The size that the cell grows to depends in part on the polysaccharides in the extracellular matrix.
		The extracellular matrix has no effect on the cells that it surrounds.
		All of these choices are correct.

2. Dynamic instability is the rapid assembly and disassembly of:

		microfilaments.
		intermediate filaments.
		microtubules.

3. Which one of the following is a characteristic shared by integrins and cadherins?

		Both are peripheral membrane proteins.

		Both are present in adherens junctions, desmosomes, and hemidesmosomes.
		The cytoplasmic domains of both proteins are connected to the cytoskeleton.

4. Which of the following is a mesh-like attachment between cells formed by binding of transmembrane proteins of one cell to the same protein type on the adjacent cell, preventing substances from passing between cells?

		a.) adherens junction
		b.)desmosome

		c.) tight junction

viridianlion889

BIO120H1 Lecture : Notes taken during lecture

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