BIO120H1 Lecture : Notes taken during lecture
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BIO120H1 Full Course Notes
Verified Note
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Document Summary
Flexible tissues (ex. blood vessels, lungs) : lungs stretches, inflating ecm full of elastin fibres, green proteins linked covalently so when stretch out, will not separate, coil and stretch and coil and stretch. basal surface of epithelial cells attached to it via focal adhesion contact. Lumen is always apical and also apical is outside body. Figure 19-53 know in detail: fibroblast can migrate not just white blood cells, both have ability to modify ecm by secreting and modifying activity of proteases. blistering diseases when basal lamina doesn"t function properly. when cannot attach cells properly to basal lamina, disease result. Link ecm to transmembrane proteins on cell surface. what is interacting with what: self assembly is how laminin stick to laminin to form large complexes, integrin and laminin attach to lamin to matrix, dystroglyan can perlecan are what. binds to type iv collagen, perlecan and nidogen .
