BIO120H1 Lecture : Notes taken during lecture

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BIO120H1 Full Course Notes
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Morphogenesis creation of 3d form in embryo. 1 cell embryo has everything it needs to: morphogenesis , cell differentiation . All based on transcriptional changes in cell encoded in genes. Cell specialization change in transcriptome, allowing cell to take on certain shape, function, Cell interaction cell signalling, cell to cell contact, adherens junctions, cell to matrix contact, etc. Cell migration movement early embryo very simple, to get more complicated, cells need to get together. Whether to proliferate or not, which cells to interact with, where should migrate . These decisions same as cancer cells made only inappropriately. I t is important to know how model organisms develop, not just humans. anything that is the same in multiple organisms = identified a core developmental mechanism. Body divides self into parts each compartment develops independently of other. development can be considered subdivision of subdivision of subdivision . Development doesn"t only occur in embryo same processes occurring all the time.