BIO130H1 Lecture Notes - Lecture 22: Basal Lamina, Extracellular Fluid, Hyaluronic Acid

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12 Jul 2017
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BIO130H1 Full Course Notes
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BIO130H1 Full Course Notes
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Bio130 lecture 22 notes: the cytoskeleton and interactions between cells and their environments. Tissues are composed of cells and extracellular matrix. How cells are organized into tissues, how cells structurally supported by components of extracellular matrix. Junctions between epithelial cells: adherens, desmosomes, provide structural support by linking cytoskeletons of cells. Tight junctions: prevent extracellular fluid from apical side from mixing with fluid on basal side. Other types of junctions allow cells to interact with extracellular matrix. 2 different types of tissues on skin: epidermis and dermis. Epidermis: special type of epithelial sheet, multiple layers of epithelial cells. Columnar epithelial cells anchored into basement membrane/basal lamina (special kind of extracellular matrix) Epitheilal cells connected to each other, connection supported by cell-to-cell anchoring junctions. Underlying dermis (different type of tissue, connective tissue) quite different. Rather than repeated arragenement of cells, dermis has fewer cells, tend not to be connected to each other.