BIO130H1 Lecture 9: BIO130 Section 2 Lecture 9 and 10.docx

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14 Apr 2012
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BIO130H1 Full Course Notes
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Lecture 9 and 10: interactions b/w cells and their environments. Microvillus of epithelial cells increase sa and allow intake from intestine. Mechanical stresses are transmitted from cell to cell by cytoskeleton filaments anchored to cell matrix and cell- cell adhesion site. Extracellular matrix directed bears mechanical stresses of tension and compression. 2 main types of tissues: epithelial tissue: (cells polar) eg. intestinal lining, skin epidermis. Limited ecm (a thin basal lamina that underlies the basal domain. Cytoskeletal filaments provide resistance to mechanical stress. Cells are attached to each other by cell junctions: connective tissue: eg. bone, tendon. Cells are rarely connected to each other. Plentiful ecm which provides resistance to mechanical stress. Ecm (not polar) cells are attached to ecm different types of junctions b/w cells: anchoring junctions (epithelial cells): anchor cells to each other, allow cytoskeletal filaments from one cell to connect to other. Hemidesmosome anchors intermediate filaments in cell to extracellular matrix.

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