BIO130H1 Lecture Notes - Lecture 13: Facilitated Diffusion, Cytosol, Sodium-Potassium Alloy
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BIO130H1 Full Course Notes
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Classes of membrane transport proteins: uniporters, symporters and antiporters, atpases. Small, uncharged polar molecules are generally not able to pass through(except for water)o not as fast as hydrophobic molecules. Movement via simple diffusion through the lipid bilayer: 1) high concentration to low concentration. Down the concentration gradient: 2) more hydrophobic or nonpolar the molecule. These require membrane proteins for transport: arrow denotes proteins. Membrane transport proteins are all multipass transmembrane proteins. Transport polar and charged molecules: note: does not mean they are all multiple alpha helices, protein lined path across cell membrane, ions, sugars, amino acids, nucleotides, various cell metabolites, different transport proteins. Each transport protein is selective: transport specific class of molecules. Concentration gradient (the arrow is not necessarily the direction of transport) Passive transport goes down the concentration gradient. Active transport moves against the concentration gradient: does not require energy, requires energy, channel proteins do not interact a lot, do not bind strongly to the transported.
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