BIO130H1 Lecture Notes - Lecture 8: Electrochemical Gradient, Alpha Helix, Atp Hydrolysis

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9 Mar 2016

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Impermeable to large uncharged polar molecules and ions, but can be transported with the help of membrane proteins. Membrane transport proteins: multipass transmembrane proteins (not all alpha helices), a protein lined path across the cell membrane, transport polar and charged molecules, each is selective, transports a specific class of molecule, but the specificity can vary. Passive transport: down concentration gradient, doesn"t require energy. Channel proteins: don"t interact with molecule a lot, don"t bind strongly to the molecule, don"t change conformation much. Cotransporters: one molecule down gradient, one molecule against the gradient. Light driven pump: use light energy, against gradient. Electrochemical gradient: concentration gradient plus membrane potential (electrical gradient), like charges repel. Transporter proteins: bind a specific solute, go through conformational change transporting molecule. Uniport: passive, one molecule down electrochemical gradient, direction of transport is reversible depending on concentration: glut: transports glucose down the electrochemical gradient, works in both directions (glucose in and out)

Related Questions

3. In an aqueous environment, the phospholipids of a membrane____.

a) are arranged in a single layer

b) are arranged in a bilayer with the polar heads of each layerlocated at the surface

c) are arranged in a bilayer with the fatty acid tails locatedat the surface

d) are arranged in a bilayer but the phospholipids have nospecific orientation

e) dissolve

4. which of the following molecules demonstrate dual solubilitycharacteristics

a) sterols only

b) proteins only

c) phospholipids only

d) sterols and phospholipids

e) sterols, phospholipids, and proteins

5. The "mosaic" part of the fluid mosaic model refers to themembrane ____.

a) proteins

b) phospholipids

c) cholesterol

d) functions

e) layers

9. Transport of a molecule across a cell membrane by facilitateddiffusion ____.

a) does not exhibit specificity for a particular type ofmolecule

b) requires the input of energy

c) depends on a concentration gradient

d) goes against the concentration gradient

e) allows non-polar uncharged molecules to diffuse across amembrane

13. A transport system in which transport of an ion in onedirection provides the energy for active transport in the oppositedirection is known as ____.

a) primary active transport

b) active diffusion

c) secondary active transport

d) cotransport

e) osmosis

14. Cells undergo exocytosis ____.

a) to pump protons down a concentration gradient

b) when replicating

c) to secrete protein and wastes from the cell

d) to ingest nutrients

e) as a means of cellular protection

15. What is the molecular basis of familialhypercholestremia?

a) HDL enters cells using a specific receptor on the cellsurface

b) LDL enters cells using a specific receptor on the cellsurface

c) HDL exits cells using a specific receptor on the cellsurface

d) LDL exits cells using a specific receptor on the cellsurface

e) receptor-mediated exocytosis

16. Carrier molecules are utilized for ____.

a) active transport only

b) passive transport only

c) both active and passive transport

d) osmosis

e) transport of all types of molecules

17. All of the following are functions of integral membraneproteins EXCEPT ____.

a) transport of polar molecules

b) reception of chemical signals form other cells

c) cell division

d) recognition of other cells as being "like"

e) cell-cell binding

olivecod348

Explain the cell theory; know the three basic tenets of the theory.

All cells have to carry out certain functions, what do all cells have in common?

Compare/contrast an Eukaryotic vs a Prokaryotic cell type.

Understand the concept of selective toxicity. What do all effective targets of an antimicrobial agent have in common? What are some characteristics of Prokaryotic cells that can be targeted?

Explain the unity and diversity of prokaryotic cells in terms of evolutionary theories.

Describe the three basic shapes (morphologies) of bacteria.

What are the functions of the plasma membrane, how does the structure of the plasma membrane aid in carrying out these functions?

Describe the fluid mosaic model of the plasma membrane. Draw out the plasma membrane, include the phospholipid bilayer (indicating polar/hydrophilic and nonpolar/hydrophobic components) and peripheral and integral proteins. Also indicate the intracellular (cytoplasmic) and extracellular regions.

What are the functions of the components of the plasma membrane? Phospholipids, proteins?

Transport. Compare/contrast the following mechanisms of transport in terms of the types of molecules transported, with or against the concentration gradient, if any Energy input is required, if a transport molecule is involved, and if Euk and or Prok use this mechanism.

Osmosis (explain the role of aquaporins)

Diffusion

Facilitated Diffusion

Active transport (proton motive force / ATP binding cassette system)

Group translocation

Please help! Not sure about these questions..thanks

Which can cross the phospholipid bilayer of a membrane without assistance from transport proteins?

	A.	Ions such as Na+.
	B.	Small hydrophobic molecules such as O2.
	C.	Small hydrophilic molecules such as glucose.
	D.	Any small molecule or ion.

QUESTION 2

Which transport process requires a cell to expend energy?

	A.	Moving a solute up its concentration gradient.
	B.	No transport processes require energy.
	C.	Moving a solute either up or down its concentration gradient.
	D.	Moving a solute down its concentration gradient.

QUESTION 3

Imagine a cell whose membrane is permeable to water, but impermeable to solute X. If solute X is more concentrated outside the cell than inside, which way will water move by osmosis?

	A.	Water will not move in either direction, in or out of the cell.
	B.	Water will move equally in both directions, in and out of the cell.
	C.	Water will leave the cell.
	D.	Water will enter the cell.

QUESTION 4

The cellular structure that encloses the DNA/genes is the

		ribosome.
		plasma membrane.
		nucleus.
		mitochondrion.

QUESTION 5

The part of metabolism that builds larger, more complex molecules or structures from smaller, simpler components is

	A.	anabolism.
	B.	catabolism.
	C.	catalysis.
	D.	hydrolysis.

QUESTION 6

In an exergonic reaction

	A.	the reactants have more energy than the products, so energy is absorbed.
	B.	the reactants have more energy than the products, so energy is released.
	C.	the reactants have less energy than the products, so energy is released.
	D.	the reactants have less energy than the products, so energy is absorbed.

BIO130H1 Lecture Notes - Lecture 8: Electrochemical Gradient, Alpha Helix, Atp Hydrolysis

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