BIO220H1 Lecture Notes - Lecture 16: Lactase Persistence, Lactose Intolerance, Coevolution

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A pair of species, caused by selection imposed by each other. The two sexes, caused by selection imposed by each other. Human agricultural coevolution: reciprocal evolutionary responses in: Humans and their agricultural species, caused by selection imposed by each other. Human-agricultural coevolution: evolution by ns is a genetic and ecological process. Lactase persistence in human populations: in many humans of european origin, lactase production persists through adulthood. Evolution in european cattle farming cultures: observation: In european populations, changes in the lactase gene strongly correlated with the ability to digest lactose as an adult: hypotheses: Predictions: if substitutions in the lactase gene cause lactase persistence, then we would predict: Other human populations practicing dairy agriculture should have lactase persistent phenotypes. We should see genetic evidence of past selection at the lactase gene in the human genome. Results: lactase digestion: african cultures with dairy farming also have distinctive forms of the lactase gene.

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