BIO230H1 Lecture Notes - Lecture 5: Limb Bud, Limb Development, Morphogen
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BIO230H1 Full Course Notes
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Bio230 lecture 5 - tissue patterning (nov 2) Last class we talked about morphogenesis (how tissues are shaped) Start with cells that are equal and have the same genomes. When one cell are differentiated from the rest, changes its gene expression. There is a difference in the cell to begin with. Red dots on one side of cell only. As (cid:272)ell di(cid:448)ides, o(cid:374)e daughter (cid:272)ell re(cid:272)ei(cid:448)es red dots, the other does(cid:374)"t. Cell differentiation came from differences within the cell. Cells can be born identical to one another. One daughter cell is born into an environment that is different than sister cell. Differe(cid:374)t e(cid:374)(cid:448)iro(cid:374)(cid:373)e(cid:374)t = re(cid:272)ei(cid:448)es sig(cid:374)als that other (cid:272)ell does(cid:374)"t. Differences in gene expression between different sets of cells. = symmetric division followed by different signals acting on them after birth. Asymmetric cell division and cell differentiation in c. elegans. Every single cell division from fertilized egg to adult worm is mapped.
