BCH210H1 Lecture Notes - Lecture 26: Glycogen Synthase, Membrane Potential, Glut2

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BCH210H1 Full Course Notes
BCH210H1 Full Course Notes
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Is a gpcr: 7 transmembrane helices, multiple enzymes are activated in a signalling pathway at one time which takes some time. Glycogenolysis: glycogen breakdown is a phosphorolysis reaction, releasing glucose 1-phosphate from non-reducing ends, glycogen phosphorylase is activated by phosphorylation. Ser^14 but also allosterically regulated by atp/amp and glucose 6-phosphate: caveat: glucose 1-phosphate cannot be used directly in glycolysis it must be converted to glucose-6-phosphate, structure must be changed, isomerization reaction, different pathways for glycogen production. Liver (cid:2163)(cid:2203)(cid:2197)(cid:2201) (cid:2778) (cid:2172)(cid:2190)(cid:2197)(cid:2201)(cid:2198)(cid:2190)(cid:2202) (cid:2163)(cid:2203)(cid:2197)(cid:2201) (cid:2172)(cid:2190)(cid:2197)(cid:2201)(cid:2198)(cid:2190)(cid:2202) (cid:2163)(cid:2203)(cid:2197)(cid:2201) (cid:2172)(cid:2190)(cid:2197)(cid:2201)(cid:2198)(cid:2190)(cid:2202)+(cid:2164)(cid:2779)(cid:2171) (cid:2163)(cid:2203)(cid:2197)(cid:2201)+(cid:2172)(cid:2191: via a liver enzyme used in gluconeogenesis (gng) glucose-6-phosphatase, glucose leaves the liver and enters the bloodstream, liver glycogen provides glucose for the brain, important mechanism. Receptor is absorbed into the membrane by vesicles and degraded for the use of their amino acids. New receptors will have to be made. Insulin signalling (anabolic: following a meal, glucose can stimulate the b- cells of the pancreas to secret insulin.