BCH210H1 Lecture Notes - Lecture 13: Methyl Group, Membrane Lipids, Close-Packing Of Equal Spheres

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BCH210H1 Full Course Notes
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BCH210H1 Full Course Notes
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Dr. roman melnyk: senior scientist molecular medicine program, the hospital for sick children, assistant professor department of biochemistry, university of toronto roman. melnyk@sickkids. ca. Lipids and membranes: lecture 1 biological lipids: structures and functions, lecture 2 membrane lipids: assembly and dynamics, lecture 3 membrane protein properties, lecture 4 membrane protein structures, lecture 5 membrane protein function. Proteins are still the fundamental workhorses of the cell and of the membrane. Protects cells from the outside world: creates specialized compartments that can perform different functions. Form selectively-permeable barriers, allowing certain things in and out: disease states with malfunction in permeability via channels and transporters, lipids can be potent signals traveling through the blood to mediate different things. What are lipids: chemically diverse group of molecules, defined by their physical properties, (cid:1373) solubility in water, solubility in non-polar solvents. Biological lipids: fatty acids are major components of many lipids. Phospholipids, sphingolipids, glycolipids, sterols: lipids that are in the membranes that help maintain integrity of cells.