BCH210H1 Lecture Notes - Lecture 27: Insulin, Reaction Mechanism, Anabolism

• School: UTSG
• Department: Biochemistry
• Course: BCH210H1
• Professor: Stavroula Andreopoulos

Document Summary

Garrett et al: chapter 17. 1-17. 7, end of chapter problems: 1, 3, 9, 11, 13, review questions posted on blackboard. 10 steps, but focus on the steps that generate energy (atp and reduced coenzyme nadh) some chemical logic behind some reaction mechanisms. Focus on steps that are regulated, which determines whether the pathway is on or off. G1p, converted to g6p for glycolysis: or, glucose enters muscle cells through glut4 transporters to be metabolized into energy, glycolysis takes place in all cells (glycogen is specific to muscle and liver) First stage/phase is the first 5 steps: energy input phase, require energy, require 2x atp per glucose, at the end of stage 1, we have 2 molecules of gap. In stage 2, we generate more energy (atp and nadh: generate 4 atp, because the last 5 steps occur twice. Investment stage and energy output stage: all takes place in the cytoplasm. Pyruvate dehydrogenase complex (pdc), krebs cycle, and oxidative phosphorylation.