BCH210H1 Lecture Notes - Lecture 13: Biological Membrane, Cardiovascular Disease, Scurvy

• School: UTSG
• Department: Biochemistry
• Course: BCH210H1
• Professor: Sian Patterson

Document Summary

For melnyk"s five lectures: ch8 (8. 1-4; 8. 7-8) q2, 3, ch10, q15, 20-23, ch11 (11. 4), q11. Unsaturated and saturated fats: storage lipids, membrane lipids, signaling lipids, start of section 2. Lecture notes: biological lipids - structures and functions. Chemically diverse group of molecules defined by their physical properties. Low solubility in water and high solubility in non-polar solvents. Unlike amino acids, there is no defined structure --> defined by its properties. Fatty acids are major components of many lipids. All have the same structure with the following: Fatty acyl chain either single bonds (saturated) or contains one or more double bonds (unsat) Either "free fatty acids" or esterified to backbones. Below are different examples of a saturated fatty acid. These prefer an extended conformation (lowest energy state) rather than constantly rotating around (they are all sp3 hybridized) Most common is the saturated with no double bonds. Double bonds almost always in a cis conformation, resulting in a kink in the strucutre.