BCH210H1 Lecture Notes - Lecture 9: Lipid Bilayer, Organophosphate, Glycerol

• School: UTSG
• Department: Biochemistry
• Course: BCH210H1
• Professor: Stavroula Andreopoulos

Document Summary

The lipid bilayer: 2 molecules thick each containing a hydrophobic tail (forming the hydrophobic core) and polar head group, diameter of bilayer = (on avg. ) Phospholipid composition: fatty acid tails, glycerol backbone, phosphate (polar, hydrophilic, polar head group. Fatty acid: polar, carboxylic acid head group deprotonated @ ph=7. 4, gets priority when naming, hydrocarbons, greek naming carbon adjacent to carboxyl group = , terminal methyl group always omega ( , typically even number chain. Omega-3 fatty acids: -linolenate cis double bonds at -3, 6, and 9, eicosapentaenoate (epa) -3, 6, 9, 12, 15; form eicosanoids, docosahexaenoate (dha) -3, 6, 9, 12, 15, 18, essential because body cannot make. Fa identity determines tm: at tm: solidlike fluidlike, depends on fa length and dou, e. g. , butter highly saturated many vdw between tails so add heat to break those. Fish in desert streams: fish living in desert streams have ability to alter membrane-lipid composition between hot days and cooler nights, at night (cooler temp.