BCH311H1 Lecture Notes - Lecture 11: Pathogenicity Island, Septic Shock, Microorganism
1 Feb 2018
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Colo(cid:374)izatio(cid:374) does(cid:374)"t (cid:373)ea(cid:374) just pathoge(cid:374)s, it (cid:272)a(cid:374) e(cid:448)e(cid:374) (cid:271)e (cid:271)a(cid:272)teria. I(cid:374)fe(cid:272)tio(cid:374) is the ter(cid:373) (cid:272)olo(cid:374)izatio(cid:374) for a pathogen. 1/20 times do we go see the doctor for when we are sick. When a disease impairs the normal state, this is called a disease state. Primary infections are caused by the microbe that got you sick. Some microbe infections make us more susceptible to other infections, like hiv. Another example is measles which weakens the function of the lungs. The id50 is how many bacteria are requires to get half the population sick. Shigells is acid resistant, salmonella is less acid resistant. Incubation period is also affected by the hosts immune function and amount of microbe injested. The prodromal phae is where the pathogens make you feel under the weather before the real disease kicks in. Conalescence could be immediate, or it can take months. Carriers are hard to control because some can be asymptomatic.
