BIO120H1 Lecture Notes - Glycan, Serostatus, Cell Nucleus

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10 Dec 2012
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BIO120H1 Full Course Notes
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BIO120H1 Full Course Notes
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You need to bind to the receptor before trypsin cleavage. If you cleave first, you won"t allow it the possibility to attach well to the ace receptor. A receptor for sars-cov is ace 2 and l sine. Trypsin cleaves the s protein into s1 and s2. Circularized once into human nucleus by ligating two linear strands together. Notice there are repeat elements: we haven"t discussed this yet. Tegument full of viral proteins and crucial part of viral infection. There are some levels of new strains arising but this is a dna genome virus and dna genome viruses tend not to evolve as much as rna genome viruses. Cmv is not trouble to healthy individuals, but those who are not well such as those on immune depressant drugs. Tegument proteins are packaged inside the viral envelope and are introduced into the cell upon infection. Recent research says there may be even some viral mrnas in this tegument portion.

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