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Department
Biology
Course
BIO120H1
Professor
Jean Jiang Nash
Semester
Winter

Description
LECTURE Feb. 8, 2011 ***Read figure legends in textbook before class for next, next lecture*** Exocytosis Lipids Vesicles move to plasma membrane to deliver cargo, including lipids o Bring lipids from synthesis at ER to Golgi to vesicles Membrane proteins Secreted soluble proteins 2 types of exocytosis Constitutive always on, always functional, default o If protein is synthesized into ER lumen and has only ER signal sequence, now soluble protein, its default fault is to be secreted in constitutive secretive pathway o Be secreted Regulated e.g. insulin o Those vesicles stay in cytosol, wait for signal Constitutive secretory pathway No sorting signal ends up in cytosol So default pathway sentence should be changed for proteins with a ER signal
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