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Jean Jiang Nash

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LECTURE 10 Cell communication Unicellular organism Signal transduction cascade EGF receptor is the receptor tyrosine kinase Feeds into nucleus to alter transcription A NETWORK not linear Why is signalling important? Cyclic AMP o Nucleotide secreted by single celled organism, slime mold In rotting log in forest Divide and take over the log Eventually run out of nutrients, secrete cyclic AMP Cyclic AMP attracts each other, so all mold gets together into a slug and move out of wood This organism is at the edge of unicellular and multicellular Two types of cells stalk and spores spore flies away stalk dies Get together because theyre attracted to cAMP Cell migrates towards the source outside the cell Cell rece
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