Class Notes (839,092)
Canada (511,185)
Biology (2,229)
BIO120H1 (1,171)
Lecture 10

Lecture 10

4 Pages

Course Code
Darrel Desveaux

This preview shows page 1. Sign up to view the full 4 pages of the document.
Lecture 10 Cell Communication: General Concepts and Principles Cell Communication Through Signaling o Unicellular organisms Sense signals in growth environment Eg. High [nutrients] o Multicellular organisms Complex signaling networks Cells within organism carefully regulated Why is Signaling Important? Example: Regulation of Cell Proliferation o If cell doesnt respond appropriately cancer o Chart of major signaling pathways relevant to cancer in human cells (Figure 20-37) o Cancer misregulation of growth cells o Overactive signals regulate proliferation Why is Signaling Important? Example: Regulation of Cell Movement o Slime Mold (unicellular) Attracted to cAMP chemotaxis moves toward high concentration of chemical Signal for single cells to aggregate to form slug o Micropipette with cAMP Movement by extending a new pseudopod Signal Molecules and Receptors o 1) Cell surface receptors Bind to hydrophilic ligand o 2) Intracellular receptors Bind to hydrophobic signaling molecules Transported by carrier proteins in extracellular fluid and deliver to cells Because not soluble Classes of Cell Surface Receptors in Animals o 1) Ion-Channel-linked receptors (ligand gated ion channels) Eg. Regulated by neurotransmitters o 2) G-protein-linked receptors (GPCR) Largest family in animals >800 genes in human genome Receptors to visual, taste, smell, and many other neurotransmitters o 3) Enzyme-linked receptors
More Less
Unlock Document

Only page 1 are available for preview. Some parts have been intentionally blurred.

Unlock Document
You're Reading a Preview

Unlock to view full version

Unlock Document

Log In


Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.