BIO120H1 Lecture : Notes taken during lecture

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redtermite204

15 Mar 2011

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BIO120H1 Full Course Notes

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Lecture 17 extracellular matrix and cell motility. human fibroblast cells grown in tissue culture. Tight junction so things cannot pass between cells. cell cell anchoring junction adhering junction actually holds cells together. channel forming gap junctions allow small materials pass from cell to cell. Focal adhesion below the left hand bottom paragraph: contact btw basal surface and extracellular matrix, important for cell migration. Ecm drawing of basal surface of cell. epithelial cell layer apical at top. Two major kind of ecm (basal lamina) (connective tissue) . muscle contract pulls on basal lamina, which pulls on connective tissue, which pulls on bone. capillary endothelial cells attached to basal lamina: kidney has lining of tubules no tight junctions between cells allows filtering function so blood cells not found in urine. Together v strong structure, having tensile strength and resistance to compression www. notesolution. com.

Related Questions

1. How does the extracellular matrix affect a cell that it surrounds? (Select all that apply.)

		The cell's shape depends in part on the structure and composition of the extracellular matrix.
		The genes that the cell expresses depend in part on the types of proteins in the extracellular matrix.
		The size that the cell grows to depends in part on the polysaccharides in the extracellular matrix.
		The extracellular matrix has no effect on the cells that it surrounds.
		All of these choices are correct.

2. Dynamic instability is the rapid assembly and disassembly of:

		microfilaments.
		intermediate filaments.
		microtubules.

3. Which one of the following is a characteristic shared by integrins and cadherins?

		Both are peripheral membrane proteins.

		Both are present in adherens junctions, desmosomes, and hemidesmosomes.
		The cytoplasmic domains of both proteins are connected to the cytoskeleton.