BIO130H1 Lecture Notes - Lecture 10: Intron, Ribose, Tata Box

50 views3 pages
31 Jan 2018
School
Department
Course
ash-mr18 and 40043 others unlocked
BIO130H1 Full Course Notes
31
BIO130H1 Full Course Notes
Verified Note
31 documents

Document Summary

It"s the sg(cid:373)a fa(cid:272)to(cid:396) that gi(cid:448)es the spe(cid:272)ifi(cid:272)it(cid:455) to (cid:449)he(cid:396)e the (cid:396)(cid:374)a (cid:449)ill (cid:271)i(cid:374)d to the d(cid:374)a. The(cid:396)e is a little (cid:271)it of (cid:373)elti(cid:374)g o(cid:374) the heli(cid:454) so the (cid:396)epli(cid:272)ati(cid:374)g (cid:373)a(cid:272)hi(cid:374)e(cid:396)(cid:455) (cid:272)a(cid:374) get i(cid:374). There are several abortive mechanisms in rna polymerase. It will make 5-6 nucleotides, then stop, and some rnas will cast off. Once it gets past 10, there is a conformational change in the core rna polymerase and the sigma factor is released, and the rna polymerse is transcribing the dna until it hits the termination point. There are 2 mechanisms for termination, one is called ro dependent. There is a protein called ro haped like a ring, and it wil dislodge the mrna. The other is ro independent, and this one depends on the dna sequences. The termination sequence is a gc rich, followed by at rich. We make less than 10, its inefficnent, but once it gets going its highly processive,

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related textbook solutions

Related Documents

Related Questions