BIO130H1 Lecture Notes - Lecture 4: Eucalyptus Globulus, Tennis Ball, Melas Syndrome
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BIO130H1 Full Course Notes
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Document Summary
Dna recovered from bones from a 38000 year old site in croatia. Modern humans with non-african ancestral genomes contain approx. Partial sequence analysis shows only 78 amino acid variants in protein coding genes that might impact on function. The building blocks of life page 4 bacteriophage. The building blocks of life page 10 nucleoid topoisomerase. Topoisomerase are enzymes that wind and unwind dna. All are packaged in a small area and should be easily accessible. Geometric equivalent of packaging 40 km of find thread into. Total length of dna in a human body is 2e10 km. Take a probe that connects to a certain sequence and it lights up. Each chromosome contains a single, long, linear dna molecule and associated proteins. Chromatin is tightly packaged, but the dna must remain accessible for transcription, replication and repair. In general, nucleosome refers to the linker dna also. 147 and 80 aren"t 200 so it depends on your definition of nucleosome.
