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Lecture 3

Coleman Lecture Three

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Department
Biology
Course
BIO130H1
Professor
John Coleman
Semester
Fall

Description
Lecture ThreeMolecular Interactions interactions between individual molecules usually mediated by noncovalent attractionsindividually very weak forces can sum to generate strong binding between molecules RNA synthesis transcriptionprotein synthesis translation Nucleic acid chains DNA synthesized from deoxyribonucleoside triphosphates known as dNTPsRNA synthesized from ribonucleic triphosphatesNTPs Nucelotides linked by phosphodiester bonds Base pairing 1 holds DNA helix together 2 AT bases 2 HbondsGC bases 3 Hbonds Three forces keep DNA together Hbonds Van der Waals attractions Hydrophobic attractionsstrands in double helix are ANTIPARALLEL one strand is 53 its partner is 35 Two ends of DNA composed of5phosphate group PO4 3hydroxyl group OHSequences of two strands are complementarycan be unzipped important for DNA replicationRNA synth
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