BIO130H1 Lecture 8: Lecture 8

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25 Mar 2012
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BIO130H1 Full Course Notes
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Lecture 8: transcription 2: structure of a gene, rna polymerases, transcription of protein coding genes, rna processing o. An expanded repertoire of rnas to generate o o o. In eukaryotes we have rna species which extend well beyond those normally required for simply production of polypeptides. To make all these different rnas you also need different rna polymerases. They are being used by the cell at particular stages of post transcription or translation regulation by blocking either the translation of specific rnas or by binding to existing rnas through complimentary base pairing. Rna polymerase 1 is involved in primarily in ribosomal rna gene production. Each of these rnaps is a multi-subunit protein. Each is responsible for transcription of different sets of rnas. The 5 subunit complexes (beta, beta", alpha1, alpha2, omega) are all you need to produce bacterial functional rna polymerase. Variety of other subunit complexes for eukaryotic rna polymerases.

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