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Lecture 4

Coleman Lecture Four

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Department
Biology
Course
BIO130H1
Professor
John Coleman
Semester
Winter

Description
Bio130 Lecture 4Packaging of DNA in the cellnon packaged state even small prokaryotic genome would occupy a portion of cell volume much more in eukaryotes in prokaryotes when DNA and protein form NUCLEOID when bound together Hybridizationtechnique that measures degree of genetic similarity between pools of DNA sequences used to determine genetic sequence between two speciescolor karyotes color determined by shape color and informationfluorescent dye colors chromosomeseach chromosome contains linear DNA with associated proteinschromatin tightly packed DNA accessible for transcription replication repairdynamic Isolation of nucleosome Histones small proteinsrich in lysineargininepositive charge neutralizes negative charge of DNAfour core histone proteins H2A H2B H3 H4 pair of each in octamer core are linker histone H1Heterochromatin highly condensed chromosomesfound in mitoticmeiotic chromosomescentromerestelomeric regionsone of Xchromosome in human females
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