BIO130H1 Lecture Notes - Lecture 5: Dna Ligase, Deoxyribonucleoside, Helicase

• School: UTSG
• Department: Biology
• Course: BIO130H1
• Professor: Jane Mitchell

Document Summary

Unidirectional growth of single strands of two starting points (on both strands at once 3" to 5") ex) linear virus. Unidirectional growth of two strands from one starting point (3" to 5" on one strand and then 3" to 5" again on the partner strand) ex) some plasmids. Bidirectional growth from one starting point ex) eukaryotes and bacteria clicker question. Two possibilities: always start from the same location on dna. Recognized by and binding initiator proteins: random start. How many origins of replication: single--bacteria, multiple eukaryotes. *plasmid: a small circle of bacterial dna that is independent of the main bacterial chromosome. Plasmids often contain genes for drug resistances and can be transmitted between bacteria of the same and different species: used in genetic engineering. *yeast with ars replicate even in the absence of histidine. circular genomes ppt12. Synthesizing is always in 5" to 3" direction following 3" to 5" of parent strand.