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Lecture 7

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Department
Biology
Course
BIO130H1
Professor
Jane Mitchell
Semester
Winter

Description
Lecture 7 Ppt2 [The Cytoskeleton:] •Provides structural support •Positions organelles •Directs vesicular transport •Involved in locomotion (ex)sperm cell w flagella tail,, cell crawling) •Required for cell division *cytoskeleton is not rigid, it is dynamic *(the cytoskeletons) cilia, flagella are close structure for moving Ppt4 [Three types of filaments form the cytoskeleton] •Microfiloaments: –made up w actic proeins –Diameter: 5-9nm •Intermediate Filaments: –made up w Intermediate filament proteins -made up w individual protofiliaments -rope like, can stretch, flexible –Diameter: 10nm •Microtubules: –make up w tubulin proteins -made up w individual protofiliaments –Diameter: 25nm *each function are different, they work together Ppt5 Ppt6 [Limits of Light Microscopy] •The light microscope has a resolution limit: –Due to diffraction (light bends) –Based on the wavelength of light –~250 nm (microtubules have a diameter of 25 nm) So can’t see the structure of cytoskeletons Electron microscope : –Electrons, shorter wavelength –Resolution: <10 Angstroms (better resolution) (>250x better resolution) -can absorb the cytoskeleton structure *can see the dynamic! Not LIVE Ppt8 [Cytoskeleton is a dynamic structure!] Examples
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