BIO230H1 Lecture 6: Lecture 6 Readings
42
BIO230H1 Full Course Notes
Verified Note
42 documents
Document Summary
An mrna sequence is decoded in sets of three nucleotides. Translation: process by which the sequence of nucleotides in a mrna molecules directs the incorporation of amino acids into protein. Genetic code: set of rues specifying the correspondence between nucleotides triplets (codons) in dna or rna and amino acids in proteins. Codon: three consecutive nucleotides in rna which specifies either one amino acid or a stop to the translation process. Each amino acid added to growing end of polypeptide chain is selected by complementary base pairing between anticodon on its attached trna molecule and next codon on mrna chain. Codon specifies an amino acid to be added on to the polypeptide chain. Nucleotide sequences in mrna singla where to start protein synthesis. It always carries the amino acid methionine, forming the complex met-trnai. Eucaryotic initiation factor (eif): protein that helps load initiator trna on to the ribosome thus initiating translation. Quality control mechanisms act to prevent translation of damaged mrnas.
