BIO270H1 Lecture Notes - Lecture 4: European Route E60, Cytochrome C Oxidase Subunit Ii, Hydrophile
Document Summary
Cell signaling communication between cells: everything animals do involves communication, messenger is sent and target cell must respond to message signal has to be transported to a cell with its matching receptor. Types of cell signaling: direct, direct cell signaling. Indirect: releases chemical messengers, carried in extracellular fluid, exocrines are secreted to the environment. 6 classes of chemical messengers: peptides (most known hormones, steroids (most known hormones, amines (most known hormones, fatty acid derivatives, purines, gases structure of messenger effects the signaling mechanism. T4 is converted to t3 in peripheral tissues. T4 half life is greater involved in regulation of metabolic rate, growth, development synthesized in thyroid gland by iodination. Tyrosine resides in thyroglobulin (hydrophilic), it is iodinated and covalently linked, vesicles fuse with lysosome, enzyme cleaves thyroglobulin and released t3 and t4 lipophilic diffuse into blood, carrier protein transports to target cell.
