Class Notes (809,632)
Canada (493,758)
Biology (2,220)
BIO270H1 (61)
Lecture 3

Lecture 3.docx

3 Pages
Unlock Document

University of Toronto St. George
Chris Garside

Lecture 3  Cellular Membrane o Selectively permeable membrane with 2 primary functions o 1. Isolate cellular from the environment o 2. Organize intracellular pathways into compartments  Membrane structure o Phospholipids  Structural support  Polar head and tails o Sphingolipids  Electrical properties o Glycolipids  Communication o Cholesterol o Protein  Membrane heterogeneity o Lipid rafts  Temperature and membrane fluidity o Environmental conditions o High temperature: phospholipids are far apart o Low temperature: phospholipids are close together  Membrane Protein o Integral membrane protein: tightly bound; embedded in membrane o Peripheral membrane protein: integral membrane proteins of glycolipids  Membrane Transport o Passive diffusion  Lipid soluble molecules  No energy  No transporter  High to low o Facilitated diffusion  Hydrophilic molecules  No energy transporter  Ion channels: small pores for specific ions, open and close and “gated”  Porins: larger molecules  Permeases: limit molecules and changes conformation o Ion channels  Voltage-gated: change in voltage  Ligand-gated: separates ligand binds  Mechanogated: responses to the movement in the cell o Active Transport  Energy  Low to high  Primary active transport: one molecule  P-pump: pump specific ions (Na+, K+ and Ca2+)  F-type and v-type: pump H+  ABC type: carry organic molecules  Secondary active transport: two molecules transported  Antiport/ exchanger: move molecules in different directions  Symport/ cotransporter: molecules same direction  Electrical Gradients o All chemical gradients o Electroneutral carriers: transport neutral molecules/exchange in an equal number of mol
More Less

Related notes for BIO270H1

Log In


Don't have an account?

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.