CSB325H1 Lecture Notes - Lecture 3: Grb2, N-Terminus, Protein C
11 Apr 2017
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Page 3: 1 step for glutamic acid to gaba. In many places in the brain, gaba and glutamic acid have opposite effects. Pink benzene ring with two hydroxyls attached: know catechol group. A. 1: don"t memorize structures, do memorize synthesis pathway. If dopamine hydroxylase (enzyme) isn"t present, pathway ends at dopamine. Page 5: don"t memorize the structures, do understand the pathway. A. 2: found entirely in nervous tissue, not outside the nervous system. Page 6: largest class of hormones that we know of, named after formation of peptide bond. B. 1. a: two aa = dipeptide, 3 aa = tripeptide, when a peptide becomes long enough to fold in on itself and create tertiary structure, generally consider a protein (~60. Have to heat to 90 in hcl to break it in the laboratory. But distinguishing between the two is not clear cut. But larger peptides that act like proteins and smaller proteins that act peptide-like. Page 7: contain a huge amount of information.
