CSB327H1 Lecture Notes - Lecture 2: Type Ii Collagen, Type Iv Collagen, Adamts
2 Apr 2013
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Csb327 lecture 2 notes molecular organization and classification of collagens (september. Type i collagen will be used as the prototype for fibrillar collagens. Type i collagen is the dominant collagen in the skin and bone. 3 supramolecular assemblies of collagens based on rotary shadowing electron microscopy. Different collagens are classified by the superstructures that they form. Type iv collagen is the signature collagen of basement membrane, which forms a network. Facit collagens interact with type i collagen and promote proper assembly of fibrils. The chain composition of type i collagen is. This means that type i collagen is a blend of 1 and 2 chain. This means that you have a heterogeneous polymer. The molecular weight shows you that they are the same length in the fibril analysis. Type i is almost ubiquitous, but more abundant in bone and so on. 1(i)2 2(i) heterotrimer means you have two 1-chains of type i collagen and one 2-chain of type i collagen.
