CSB332H1 Lecture Notes - Lecture 7: Electrophoresis, Pipette
27 Feb 2012
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Csb332h1s l7; jan, 30, 2012: conductance = slope of iv curve, not absolute conductance, use curve to look at how conductance depends upon membrane pot. Plotting current amplitude against membrane pot on x axis. Slope less at -100 and 50 mv holding pot than at more (+) values. Large conductance at lower curve where slope shallow, just changes small amt w change in membrane pot. Slope shows how much conductance depends on. Ex. at -3, conductance small, small current, but conductance still greatly depends on membrane pot (ex from -2 to +25) membrane pot. Illustrating where synaptic delay comes from: what we require to induce neurotransmitter release , delay larger btwn 2&5ms on avg, larger than could be from diffusion alone. Shows voltage channels alone can elicit the. Shows delay btwn presynaptic depolarization black ca current and ca current need before can record postsynaptic response. Postsynaptically transmitters have to bind to open more ion channels.
