CSB351Y1 Lecture Notes - Hypervariable Region, Protease, Helicase
15 Feb 2012
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Document Summary
Hep a is part of the picornaviruses, hep c is flavivirus, (note: viruses are classified according to their genome not the organs that they target. This is why the hepatitis viruses are not all in the same family) Hep b is a class on its own. Hep d is a satellite to hep b, it is a in a class of its own; hep d is similar to a viriod. Hep g is similar to hep c. The hepatitis c was discovered in 1989; it is the first virus to be discovered at the molecular level before it was seen in electron microscope. They cloned the cdna of the virus, analyzed the sequence, and came out with all the proteins (b/c once you have the rna sequence you can translate the proteins). They do all the proteins from the sequence before they see it with the microscope.
