CSB429H1 Lecture Notes - Stem-Cell Niche, Germ Cell, Somatic Cell
19 Apr 2012
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Document Summary
In many animals (not all), there is a separation between germ line cells (which happens very early on) and the soma (all other cell types) Drosophila glc separate from soma early, and form at the posterior pole (before the soma actually begins deviding) Vasa = genetic marker of early development? (not sure) Larvae undergo morphogenesis / gastrulation (cell movements) and the pgcs end up in the midgut (early germ cells associated with midgut) These pgcs then need to move through midgut, and migrate to the mesoderm (through the midgut walls. Mesoderm (makes muscle) (for drosophila) makes the somatic part of the gonad. Development of these layers does not depend on the pgcs. Even without pgcs, you still have a somatic gonad (although no function because no germline cells) Pgcs and sgps recognize each other and they will eventually aggregate and sgps will wrap around pgcs and together they will form a nice round gonad (so they aggregate and coalesce)
