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CHM101_intro 2013.pdf

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Andrew( Andy) Dicks

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CHM 101S The Chemistry and Biology of Organic Molecules Sex, Drugs and Rock and Roll CHM101: The Chemistry and Biology of Organic Molecules Sex, Drugs and Rock and Roll Course Overview "Organic chemistry appears to me like a primeval forest of the tropics, ▯ full of the most remarkable things” ▯ Friedrich Wöhler, 1835. ▯ ▯ This is a relatively new course designed to introduce non-science students to the world of organic chemistry. It is an introductory course and no prior knowledge of chemistry is assumed. The course satisfies the “Physical and Mathematical Universes” breadth requirement status for Faculty of Arts and Science students. The overall goal of the course is aimed at developing basic scientific literacy through a discussion of the chemistry of organic molecules, and the important role these compounds play in many aspects of everyday life, medicine and technology. The course will begin with an introduction to the molecular world, and the basic principles of structure, bonding and chemical reactivity. Examples of the chemistry and biology of organic molecules will then be given, including the myriad roles these compounds play in nature and modern society.▯ ▯ ▯ CHM101: Lecturer & Course Spokesperson Professor Rob Batey ▯▯ Office: LM365 ▯▯ telephone: 416-978-5059 ▯ Email: [email protected]▯ ▯ About Your Lecturer:▯ Rob Batey was born and raised in an industrial ▯ district of England, known as "The Black Country". ▯ He graduated from Oxford University with a B.A. ▯ degree in 1988, and then moved to the Imperial ▯ ! College of Science, Technology and Medicine in ▯ London. There he worked with Prof. Willie B. Motherwell, receiving a Ph. D. degree in 1992 on the synthetic applications of free-radical rearrangements. As a post-doctoral fellow at the University of Pennsylvania with Prof. Jeff D. Winkler, he worked on approaches toward the synthesis of the anticancer drug taxol. Following a medicinal chemistry position at the Upjohn Company in Michigan, he joined the faculty at the University of Toronto in 1994. He is currently a Full Professor in the Department of Chemistry, and is the Undergraduate Associate Chair. His research interests are in the area of organic synthesis and its application to biology and medicine. His research program encompasses the development of new organic reactions, catalysis, organoboron chemistry, the synthesis of alkaloid natural products and other heterocycles, and their application in probing cellular processes and as anticancer and antibiotic agents. Outside of the University and scribbling chemical structures, he mostly enjoys spending time with his family. He enjoys eclectic movies and music, suffers the trials of England's football (soccer) team and, like many organic chemists, has some culinary pretensions. His favourite cultural figures are the grand inquisitors Cardinal Ximinez, Biggles and Fang.▯ ▯ ▯ ▯ Course Overview   Office Hours:▯ LM 365: ▯Monday 1:10–2:00 p.m.▯ ▯Wednesday 1:10–2:00 p.m.▯ ▯Thursday 3:10–4:00 p.m.▯ ▯ I will also meet with students by appointment. It is best to meet with me in my office during office hours or by appointment, rather than use email. Please do not leave all of your questions for examinations until the last minute!▯ ▯ Lectures:▯ LM 161: ▯Monday, Wednesday, Friday at 12:10 – 1:00 p.m.▯ ▯ The course meets three times per week in a large lecture room, normally with seats to spare. Please sit as close to the front of the room as possible so that you can interact with the lecturer and see the material on the blackboards. Come prepared by having read and printed out in advance any lecture notes posted online. Questions are particularly welcomed during class.▯ ▯ Tutorials:▯ LM161: ▯Mondays 4:10–5:00 p.m. The first tutorial is scheduled for Monday January 28th, 2013.▯ Tutor: ▯Elena Dimitrijevic ▯▯ Office: ▯LM618▯ Email: ▯[email protected]▯ Office ▯Tuesday and Wednesday 4:30–5:30 p.m. ▯ Course Overview   Course Web-page:▯ Available by logging on to “Blackboard” using you UTORID/password and then navigating through the "My Courses" section opening the CHM101H page. Material that will be posted on the web-site include lecture notes, website links, supplementary material and other course updates. Please check regularly for updates. Normally new lecture notes will be posted by 6 p.m. the day before lectures. You should print these out and bring them to class. Content from the handouts not discussed in class should be reviewed outside of class, and is considered part of the course content.▯  ▯ Please note that the course notes are not intended for distribution. Images used in the handouts are largely taken from the internet, are not used for profit, and are being used under fair-use guidelines.▯ ▯ Textbook and Course Aids:▯ There is no required textbook for the course. However, any general organic chemistry textbook will provide useful background information. Older edition books are fine to act as a general resource. Similarly for the most part online wikipedia entries provide a reasonable reference and glossary of terms. ▯  ▯ General reading▯ Additional reading material or assigned readings will be announced in class or on the course website. A general book I highly recommend that has discussions on chemistry and organic chemistry in particular, including some philosophical discussions is The Same and Not the Same by Roald Hoffmann, Columbia University Press, New York, 1995. Another book that discusses some modern aspects of drug discovery and its challenges is The Quest for the Cure by Brent Stockwell, Columbia University Press, New York, 2011.▯ ▯ Knowledge and Concepts that are assumed for this Course:
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